My favorite out-of-context panel from Walt Disney's Donald Duck: Christmas on Bear Mountain collection:

Don't get me wrong; I like it in context as well, where it appears in color, but during my flip-through my eyes landed on that panel in the back of the book, where comics scholars write brief synopses of the stories, and that panel is just as funny when you have no idea what's going on. Other than the fact that Donald Duck has created a vengeance weapon, of course.

(Confidential to Santa Claus: I've been very good this year. Please bring me a vengeance weapon for Christmas.)